Current State of Knowledge
نویسنده
چکیده
In the individuals previously uninfected by M.tuberculosis, about 2 to 4 weeks after the vaccination, erythema around an area of induration appears. Approximately at the site of prick of injection a nodule shows up. Within 3 to 10 days time, it softens giving rise to a pustule. Bursting of the pustule in about 2 to 5 days after its appearance results in an ulcer 4 to 8 mm in size. This painless depressed ulcer with undermined edges is soon covered by a thin crust or scab, which tends to peel off at the slightest provocation. The healing of ulcer in to a depressed, thin, shining scar with undermined edges in 4 to 6 weeks of its formation, marks the uneventful termination of sequence of occurrences at the site of BCG vaccination.
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